Whole blood gene expression and interleukin-6 levels
نویسندگان
چکیده
منابع مشابه
Interleukin-17 Gene Expression and Serum Levels in Acute Rejected and non-Rejected Liver Transplant Patients
Background: Interleukin-17 (IL-17), as a potent proinflammatory cytokine, has a critical role in post liver transplant outcomes. However, there is not much information about the effects of IL-17 cytokine on acute liver rejection. Objective: To evaluate the role of IL-17 in post-liver transplant acute rejection. Methods: Ninety seven adult liver transplant patients who enrolled in this cross sec...
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Background: IL-17 is a major cytokine player in T cell mediated leukocyte associated inflammation. IL-17 is also recognized to participate in the pathophysiology of asthma. Objective: To determine the role of IL-17 in predicting severe asthma. Methods: We obtained serum samples from asthmatic children under the age of 5-year in three different groups of mild (n=33), moderate (n=28) and severe (...
متن کاملInterleukin-6 gene expression in Castleman's disease.
Defined by histological criteria, Castleman's disease (CD) is a clinically and histologically heterogeneous syndrome. The functional status of immune cells in affected tissues may vary between the different forms of the disease. To address this question, the expression of cytokine genes in eight CD lymph nodes was analyzed by in situ hybridization. Two lymph nodes were taken from patients with ...
متن کاملInterleukin-6 receptor gene variations, plasma interleukin-6 levels, and type 2 diabetes in U.S. Women.
OBJECTIVE To examine the associations between common variations in the IL6R gene and circulating interleukin (IL)-6 levels and diabetes risk. RESEARCH DESIGN AND METHODS We determined 10 linkage disequilibrium (LD)-tagging single nucleotide polymorphisms (SNPs) (SNP1 to SNP10) for the IL6R gene in a nested case-control study of 672 diabetic and 1,058 healthy European Caucasian women (IL-6 lev...
متن کاملAssociation between nucleated red blood cells in blood and the levels of erythropoietin, interleukin 3, interleukin 6, and interleukin 12p70.
The appearance of nucleated red blood cells (NRBC) in the circulation is associated with a variety of severe diseases, and indicates a relatively poor prognosis. Whether a malfunction of the bone marrow leads to this phenomenon is as unknown as the possible role that cytokines could play in this process. We analyzed erythropoietin, interleukin (IL)-3, IL-6, and IL-12p70 in the blood of 301 pati...
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ژورنال
عنوان ژورنال: Genomics
سال: 2014
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2014.10.003